General
Preferred name
SB-714786
Synonyms
CHEMBL425190 ()
SB 714786 ()
P&D ID
PD049329
CAS
584555-10-2
Tags
available
probe
drug candidate
Drug indication
Discovery agent
Probe info
Probe type
calculated probe
experimental probe
P&D approved
Probe selectivity
protein-selective
Probe sources
Chemical Probes.org
High-quality chemical probes
Tool Compound Set
Probe targets
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
MOA Antagonist (Chemical Probes.org)
Compound Sets
9
Chemical Probes.org
sb-714786
Concise Guide to Pharmacology 2017/18
77
Concise Guide to Pharmacology 2019/20
77
Concise Guide to Pharmacology 2021/22
77
Concise Guide to Pharmacology 2023/24
77
DrugMAP
DMGHRY0
Guide to Pharmacology
77
High-quality chemical probes
PD049329
Tool Compound Set
External IDs
12
Properties
(calculated by RDKit )
Molecular Weight
412.23
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
5
Aromatic Ring Count
4
cLogP
4.29
TPSA
41.49
Fraction CSP3
0.31
Chiral centers
0.0
Largest ring
6.0
QED
0.47
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Serotonin 1d (5-HT1d) receptor
HTR1D
Target class
GPCR
Target subclass
Serotonin Receptor
Control
CANSAR149525
Source data